Opportunity Information: Apply for CDC RFA DP21 2106

Advancing Arthritis Public Health Priorities through National Organizations (CDC RFA DP21-2106) is a CDC-led cooperative agreement funding opportunity created to improve the health, functioning, and overall quality of life of adults living with arthritis. The notice frames arthritis as a major but frequently underrecognized driver of chronic disease burden in the United States, contributing heavily to pain, disability, work limitations, and reduced day-to-day quality of life. It highlights the scale of the problem, citing more than 54 million U.S. adults living with arthritis, about half of whom are working age, and projections that roughly 78 million adults will have arthritis by 2040. The opportunity also emphasizes that arthritis often co-occurs with other serious chronic conditions such as heart disease, diabetes, and obesity, and that arthritis-related limitations can make those conditions harder to manage, particularly by reducing a persons ability or confidence to be physically active.

A central theme of the program is that arthritis symptoms and limitations can be improved through routine physical activity and participation in self-management education programs, yet proven interventions remain underused. The NOFO focuses on increasing the reach and uptake of low-cost, arthritis-appropriate, evidence-based interventions (AAEBIs) that have demonstrated benefits such as reduced pain, improved function, decreased disability, and better quality of life. While these programs exist in certain pockets of the country, the CDC points to persistent gaps in public awareness, limited availability in many communities, and insufficient clarity about how and where people can access these services. As a result, the funding is aimed at expanding both the supply of AAEBI offerings and the demand for them by improving visibility, accessibility, and participation nationwide.

To accomplish this, the NOFO is designed to leverage national organizations and partners that already have established systems, technologies, distribution channels, or networks capable of reaching large segments of the adult population. The intent is to create sustainable, scalable approaches that increase awareness of AAEBIs, expand their geographic dispersion, and drive higher enrollment and ongoing engagement. In addition to public-facing expansion work, the opportunity includes support for technical assistance to state health departments, along with providing arthritis-specific consumer health information to the public. Another priority is facilitating collaborative action around osteoarthritis (OA) specifically, while also addressing health equity and social determinants of health that can influence awareness of programs, access to services, and peoples ability to adopt and maintain effective self-management and physical activity behaviors.

The NOFO also calls for the development of a national strategy aimed at healthcare providers. This provider-focused strategy is intended to complement medication-based approaches by strengthening the emphasis on nonpharmacologic supports such as self-management education and physical activity as adjuncts to clinical care. In practical terms, the CDC is signaling that better arthritis outcomes will require stronger connections between clinical settings and community-based, evidence-based programs, as well as more consistent messaging and referral pathways so that patients hear about and can act on these options.

From an administrative standpoint, this is a discretionary, non-research funding opportunity under the CDC (HHS, CDC, NCCDPHP) using a cooperative agreement mechanism, meaning awardees should expect substantial engagement with CDC in implementing the work. The CFDA number is 93.945. The award ceiling is $1,000,000, with an expected total of 7 awards. Eligible applicants are broad and include various levels of government, public and private institutions of higher education, nonprofit organizations (including both 501(c)(3) and non-501(c)(3)), tribal governments and tribal organizations, public housing authorities, for-profit organizations (other than small businesses), and small businesses. The original closing date listed for applications was April 5, 2021, with electronic submissions due by 11:59 p.m. Eastern Time on the deadline.

Overall, the opportunity is structured around a public health strategy that moves beyond acknowledging arthritis as common and disabling and instead invests in practical, evidence-based tools that help people manage symptoms and stay active. The expected impact is improved arthritis management, better functional outcomes, and higher quality of life, achieved by expanding proven community interventions, strengthening statewide and national support capacity, addressing equity barriers, and aligning healthcare provider practices with self-management and physical activity approaches.

  • The Department of Health and Human Services, Centers for Disease Control - NCCDPHP in the health sector is offering a public funding opportunity titled "Advancing Arthritis Public Health Priorities through National Organizations" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.945.
  • This funding opportunity was created on Jan 14, 2021.
  • Applicants must submit their applications by Apr 05, 2021 Electronically submitted applications must be submitted no later than 1159 p.m., ET, on the listed application due date.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $1,000,000.00 in funding.
  • The number of recipients for this funding is limited to 7 candidate(s).
  • Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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