Opportunity Information: Apply for RFA MD 26 001
The Research Centers in Minority Institutions (RCMI) Coordinating Center (U24 - Clinical Trial Optional) funding opportunity (RFA-MD-26-001) is a National Institutes of Health (NIH) cooperative agreement designed to create and support a single national coordinating center for the RCMI initiative. It is sponsored by the National Institute on Minority Health and Health Disparities (NIMHD) and is rooted in a longstanding congressional mandate established under P.L. 98-619 (the 1985 Departments of Labor, Health and Human Services, and Education and Related Agencies Appropriations Act). The core purpose is to strengthen and align the work of the RCMI network by providing centralized coordination, program-wide evaluation, and shared resources that help RCMI U54 Centers meet their overarching goals in research capacity building and minority health and health disparities science.
At a practical level, the Coordinating Center is expected to serve as the hub for activities that cut across all funded RCMI U54 Centers. This includes organizing and coordinating network-wide efforts, facilitating communication and collaboration among centers, and supporting consistent approaches to shared needs across the consortium. A major element is prospective evaluation of the overall RCMI program, meaning the Coordinating Center is not only tracking what has happened, but also building systems to assess progress and outcomes over time in a structured way. In addition to supporting the U54 Centers, the Coordinating Center is positioned as a national resource, responding to requests and information needs that can come from RCMI site leadership and key personnel, NIMHD and NIH staff, the broader scientific community, and members of the public.
The award mechanism is a U24 cooperative agreement, which typically indicates substantial NIH program involvement compared with a standard grant. The notice specifies “Clinical Trial Optional,” meaning the project may include a clinical trial if it fits the Coordinating Center’s aims, but a clinical trial is not required. The opportunity is categorized as discretionary funding in the health area and is associated with CFDA number 93.307. The funding is structured around making one expected award, with an award ceiling of $3,500,000, signaling that NIH intends to fund a single organization to carry out these national coordinating responsibilities at scale.
Eligibility is broad across many U.S.-based organization types, including various levels of government (state, county, city or township, and special districts), public and state-controlled institutions of higher education, private institutions of higher education, independent school districts, federally recognized Native American tribal governments, other tribal organizations, public housing authorities/Indian housing authorities, nonprofits (both with and without 501(c)(3) status, excluding institutions of higher education in those nonprofit categories), for-profit organizations other than small businesses, small businesses, and other eligible entities as defined in the funding notice. However, the opportunity places clear limits on foreign involvement: non-U.S. entities are not eligible to apply, non-U.S. components of U.S. organizations are not eligible, and foreign components (as defined in the NIH Grants Policy Statement) are not allowed. Applicants are directed to consult the NOFO’s Section III for detailed eligibility requirements and any additional conditions that govern who can apply and under what circumstances.
Key logistical details include an original closing date of August 7, 2026, and a posting/creation date of July 8, 2026. In short, this opportunity funds one national center to coordinate and evaluate the RCMI program, unify and support the activities of RCMI U54 Centers, and provide a responsive, program-wide infrastructure that can serve NIH, participating institutions, researchers, and the public while remaining entirely U.S.-based in its applicant and component structure.Apply for RFA MD 26 001
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Research Centers in Minority Institutions (RCMI) Coordinating Center (U24 - Clinical Trial Optional)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.307.
- This funding opportunity was created on 2026-07-08.
- Applicants must submit their applications by 2026-08-07. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $3,500,000.00 in funding.
- The number of recipients for this funding is limited to 1 candidate(s).
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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Frequently Asked Questions (FAQs) - RCMI Coordinating Center (U24 - Clinical Trial Optional) (RFA-MD-26-001)
What is this funding opportunity?
This opportunity funds the Research Centers in Minority Institutions (RCMI) Coordinating Center under a U24 cooperative agreement (Clinical Trial Optional). The goal is to create and support a single national coordinating center for the RCMI initiative.
What is the FOA number for this opportunity?
The funding opportunity announcement (FOA/NOFO) number is RFA-MD-26-001.
Which agency and institute sponsor this opportunity?
This is a National Institutes of Health (NIH) funding opportunity sponsored by the National Institute on Minority Health and Health Disparities (NIMHD).
What is the main purpose of the RCMI Coordinating Center?
The Coordinating Center is intended to strengthen and align the work of the RCMI network by providing centralized coordination, program-wide evaluation, and shared resources that help RCMI U54 Centers meet overarching goals in research capacity building and minority health and health disparities science.
How many awards does NIH expect to make?
NIH expects to make one award, indicating a single organization is anticipated to serve as the national coordinating center.
What is the award ceiling (maximum funding amount) for this opportunity?
The award ceiling is $3,500,000.
What type of funding mechanism is used?
The mechanism is a U24 cooperative agreement, which generally involves substantial NIH program involvement compared with a standard grant mechanism.
Are clinical trials required?
No. The notice states "Clinical Trial Optional," meaning a clinical trial may be included if it fits the Coordinating Center aims, but a clinical trial is not required.
What kinds of activities is the Coordinating Center expected to carry out?
The Coordinating Center is expected to function as a hub for cross-center activities across all funded RCMI U54 Centers. This includes organizing and coordinating network-wide efforts, facilitating communication and collaboration among centers, supporting consistent approaches to shared consortium needs, and serving as a responsive national resource for information and support.
What does "program-wide prospective evaluation" mean in this context?
It means the Coordinating Center is expected to build structured systems to assess RCMI program progress and outcomes over time, not only reporting on past activities but also tracking and evaluating performance moving forward.
Who are the primary groups the Coordinating Center will support or respond to?
Based on the notice, the Coordinating Center is positioned to respond to the needs of RCMI site leadership and key personnel, NIMHD and NIH staff, the broader scientific community, and members of the public.
What are the RCMI U54 Centers in relation to this opportunity?
The Coordinating Center is designed to support and unify the activities of funded RCMI U54 Centers by providing centralized coordination, evaluation, and shared resources that address consortium-wide needs.
Is this opportunity considered discretionary funding, and what is the associated area?
Yes. The opportunity is described as discretionary funding in the health area.
What is the CFDA number associated with this opportunity?
The associated CFDA number is 93.307.
When was this opportunity posted?
The posting/creation date is July 8, 2026.
What is the application due date (original closing date)?
The original closing date is August 7, 2026.
What types of U.S. organizations are eligible to apply?
Eligibility is broad and includes many U.S.-based organization types such as state, county, city or township governments, special district governments, public and state-controlled institutions of higher education, private institutions of higher education, independent school districts, federally recognized Native American tribal governments, other tribal organizations, public housing authorities/Indian housing authorities, nonprofits (with and without 501(c)(3) status, excluding institutions of higher education in those nonprofit categories), for-profit organizations other than small businesses, small businesses, and other eligible entities as defined in the notice.
Are non-U.S. (foreign) entities eligible to apply?
No. Non-U.S. entities are not eligible to apply.
Can a U.S. organization include a non-U.S. component as part of the application?
No. Non-U.S. components of U.S. organizations are not eligible under this opportunity.
Are foreign components allowed at all?
No. Foreign components (as defined in the NIH Grants Policy Statement) are not allowed.
Where should applicants look for the most precise eligibility requirements and any additional conditions?
Applicants are directed to consult the NOFO's Section III for detailed eligibility requirements and any additional conditions that govern who can apply and under what circumstances.
What does it mean that this opportunity is rooted in a congressional mandate?
The notice describes the RCMI initiative as rooted in a longstanding congressional mandate established under P.L. 98-619 (the 1985 Departments of Labor, Health and Human Services, and Education and Related Agencies Appropriations Act).
What is the intended role of the Coordinating Center within the RCMI network?
It is intended to serve as the central hub for network-wide coordination, collaboration, communication, and evaluation across the RCMI U54 Centers, while also acting as a national resource that can respond to information requests from NIH, participating institutions, researchers, and the public.
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