Opportunity Information: Apply for CDC RFA GH20 2065

This funding opportunity (CDC RFA GH20-2065) is a PEPFAR-supported cooperative agreement from the U.S. Centers for Disease Control and Prevention (CDC) focused on accelerating and sustaining HIV epidemic control in Uganda's Western and West Nile regions. The overall intent is to strengthen and scale comprehensive HIV prevention, care, and treatment services in a way that not only increases immediate performance but also leaves behind a more capable, decentralized health system that can maintain results over time. While the notice lists an award ceiling of 0 for Year 1 (meaning no fixed maximum is specified per award), CDC anticipated roughly $17,000,000 in total funding for the first year, contingent on available funds, with an expectation of making up to two awards.

Programmatically, the opportunity centers on high-yield strategies that improve the full HIV service cascade: finding people with HIV (case identification), quickly connecting them to services (linkage), starting and keeping them on treatment (enrollment and retention), and achieving viral load suppression (VLS). A key emphasis is on narrowing persistent service gaps by targeting the most underserved age and sex groups and by prioritizing people and communities at heightened vulnerability to HIV infection and poor outcomes. The work is framed explicitly around epidemic control goals and measurable population-level impact, rather than stand-alone activities.

In addition to core HIV testing and treatment scale-up, the notice highlights several related priorities that are critical in Uganda's context. These include tuberculosis (TB) control and treatment (recognizing TB as a leading cause of illness and death among people living with HIV), elimination of mother-to-child transmission (eMTCT) to prevent new pediatric infections, and voluntary medical male circumcision (VMMC) as a proven HIV prevention intervention. The opportunity also calls for select services for orphans and vulnerable children (OVC), reflecting the need for wraparound support for children and households affected by HIV. Supporting functions like laboratory services and strategic information (SI) are explicitly included, underscoring that reaching epidemic control depends on reliable viral load testing and strong data systems to track performance, identify gaps, and improve quality.

A defining feature of the award is the health systems strengthening approach and the expectation of close collaboration with Uganda's Ministry of Health (MOH). Recipients are expected to build capacity at multiple levels of the public health system, particularly Regional Referral Hospitals (RRHs), District Health Teams (DHTs), and frontline health care providers. The intent is to create a sustainable, decentralized HIV response where district and facility systems can manage HIV services effectively, maintain quality, and continue improving outcomes with reduced reliance on external support.

The cooperative agreement structure also implies substantial CDC involvement beyond simply providing funds, typically through technical assistance, joint planning, and performance monitoring. Coordination with other stakeholders is described as essential, meaning awardees will be expected to align with and leverage investments from other implementing partners, donors, and government programs operating in the same geography. This is meant to reduce duplication, close coverage gaps, and support a multisectoral approach that connects clinical services with community-based prevention and support.

The outcomes are tied to the global and PEPFAR-aligned "95-95-95" targets: 95% of people living with HIV knowing their status, 95% of those diagnosed receiving antiretroviral therapy (ART), and 95% of those on treatment achieving viral suppression. In practical terms, the opportunity is asking applicants to demonstrate how they will expand access, improve service coverage, and raise quality across the HIV continuum in Western and West Nile Uganda, while strengthening labs, data systems, and district-level management so that epidemic control gains are sustained. The notice was originally posted January 8, 2020, with an original application deadline of March 8, 2020, and required electronic submission by 11:59 p.m. Eastern Time on the due date. Eligibility is listed as unrestricted, meaning a wide range of entity types could apply, subject to any additional eligibility details in the full announcement.

  • The Department of Health and Human Services, Centers for Disease Control - CGH in the health sector is offering a public funding opportunity titled "Accelerating and Sustaining HIV Epidemic Control and Related Diseases in Western and West-Nile Regions in the Republic of Uganda under the President's Emergency Plan for AIDS Relief (PEPFAR)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.067.
  • This funding opportunity was created on Jan 08, 2020.
  • Applicants must submit their applications by Mar 08, 2020 Electronically submitted applications must be submitted no later than 1159 p.m., ET, on the listed application due date.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The number of recipients for this funding is limited to 2 candidate(s).
  • Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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