Opportunity Information: Apply for PAR 24 144

The Support for Research Excellence (SuRE) Award (R16, Clinical Trial Not Allowed) is a National Institutes of Health (NIH) grant opportunity designed to strengthen research capacity at resource-limited colleges and universities by funding investigator-initiated biomedical research projects. The program supports a wide range of NIH-relevant science, including basic, social, clinical, behavioral, and translational research, as long as the proposed work aligns with NIH mission areas. A key feature of SuRE is that it is not just about producing research results; it is also meant to build a stronger, more sustainable research environment at the applicant institution by supporting faculty research programs, creating meaningful hands-on research opportunities for students, and improving the overall culture of scientific investigation on campus.

A central eligibility focus is the investigator and institutional context. SuRE is intended for faculty investigators working at eligible, resource-limited higher education institutions who are not currently supported by any NIH Research Project Grants (RPGs). The main exception is that investigators who have SuRE or SuRE-First awards are not automatically excluded on that basis alone, but otherwise the program is aimed at researchers who do not already have NIH RPG funding. The broader goal is to expand NIH-supported research participation by reaching institutions and investigators who have historically had fewer opportunities to compete for and sustain major federal biomedical research funding.

Eligible applicant organizations include public and state-controlled institutions of higher education, private institutions of higher education, and certain other qualifying institutional categories. The announcement explicitly highlights several types of institutions that are included among eligible applicants: Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISI), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), and Tribally Controlled Colleges and Universities (TCCUs). These categories reflect the program's emphasis on broadening participation and strengthening research ecosystems at institutions that often serve large proportions of students from groups underrepresented in biomedical research.

The opportunity is strictly limited to domestic applicants and domestic project components. Non-U.S. (foreign) organizations are not eligible to apply, and non-domestic components of U.S. organizations are not eligible either. In addition, foreign components, as NIH defines them in its Grants Policy Statement, are not allowed under this funding opportunity. Another major boundary is in the title itself: clinical trials are not allowed under this R16 program announcement, so proposed studies must be designed to avoid meeting the NIH definition of a clinical trial.

Administratively, this is a discretionary grant program administered by the NIH. The funding opportunity number is PAR-24-144, and it falls under multiple NIH CFDA listings (including 93.113, 93.121, 93.172, 93.173, 93.242, 93.273, 93.279, 93.286, 93.361, 93.398, 93.846, 93.847, 93.853, 93.855, 93.859, 93.866, 93.867, and 93.879), reflecting that it can align with different NIH Institutes and Centers depending on scientific topic. The opportunity was created on March 14, 2024, and the original closing date listed is January 7, 2027. The listed award ceiling is $100,000, indicating the maximum award amount referenced in the provided source data.

In practical terms, SuRE is best understood as a research-project grant aimed at helping a faculty member launch or strengthen an NIH-relevant research program in an environment with fewer research resources, while simultaneously embedding student training and mentorship into the project. Reviewers and program staff typically expect the work to be scientifically sound and feasible, but also to meaningfully contribute to long-term capacity building at the institution through sustained research activity, student development, and an improved research culture.

  • The National Institutes of Health in the education, environment, food and nutrition, health sector is offering a public funding opportunity titled "Support for Research Excellence (SuRE) Award (R16 Clinical Trial Not Allowed)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.113, 93.121, 93.172, 93.173, 93.242, 93.273, 93.279, 93.286, 93.361, 93.398, 93.846, 93.847, 93.853, 93.855, 93.859, 93.866, 93.867, 93.879.
  • This funding opportunity was created on 2024-03-14.
  • Applicants must submit their applications by 2027-01-07.
  • Each selected applicant is eligible to receive up to $100,000.00 in funding.
  • Eligible applicants include: Public and State controlled institutions of higher education, Private institutions of higher education, Others.
Apply for PAR 24 144

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Support for Research Excellence (SuRE) Award (R16, Clinical Trial Not Allowed) - FAQs

What is the SuRE Award (R16, Clinical Trial Not Allowed)?

The Support for Research Excellence (SuRE) Award is an NIH grant opportunity that funds investigator-initiated biomedical research projects while also strengthening research capacity at resource-limited colleges and universities. It supports NIH-relevant science and is designed to help build a more sustainable research environment at the applicant institution.

What is the main purpose of this funding opportunity?

The opportunity is meant to do more than produce research findings. It is intended to strengthen the applicant institution's research ecosystem by supporting faculty research programs, providing meaningful hands-on research opportunities for students, and improving the overall culture of scientific investigation on campus.

What types of research can be supported?

The program supports a wide range of NIH-relevant research, including basic, social, clinical (non-trial), behavioral, and translational research, as long as the proposed work aligns with NIH mission areas.

Are clinical trials allowed under this SuRE R16 opportunity?

No. Clinical trials are not allowed under this funding opportunity. Proposed studies must be designed so they do not meet the NIH definition of a clinical trial.

Who is this program intended for?

SuRE is intended for faculty investigators working at eligible, resource-limited higher education institutions, particularly investigators who are not currently supported by any NIH Research Project Grants (RPGs). The program aims to expand NIH-supported research participation among institutions and investigators that have historically had fewer opportunities to compete for and sustain major federal biomedical research funding.

Can an investigator apply if they currently have an NIH Research Project Grant (RPG)?

In general, the program is aimed at investigators who are not currently supported by any NIH Research Project Grants (RPGs). The provided information emphasizes this as a central eligibility focus.

Are investigators with prior or current SuRE or SuRE-First awards automatically excluded?

No. The provided information notes an exception: investigators who have SuRE or SuRE-First awards are not automatically excluded on that basis alone.

What types of organizations are eligible to apply?

Eligible applicant organizations include public and state-controlled institutions of higher education, private institutions of higher education, and certain other qualifying institutional categories.

Does the announcement highlight any specific institution types as eligible?

Yes. The opportunity explicitly highlights eligibility for several types of institutions, including Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISI), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), and Tribally Controlled Colleges and Universities (TCCUs).

Is this opportunity limited to U.S. (domestic) applicants?

Yes. The opportunity is strictly limited to domestic applicants and domestic project components. Non-U.S. (foreign) organizations are not eligible to apply.

Are non-domestic components of U.S. organizations allowed?

No. Non-domestic components of U.S. organizations are not eligible under this opportunity.

Are foreign components allowed in any form?

No. Foreign components, as NIH defines them in its Grants Policy Statement, are not allowed under this funding opportunity.

Which agency administers this grant?

This is a discretionary grant program administered by the National Institutes of Health (NIH).

What is the funding opportunity number?

The funding opportunity number is PAR-24-144.

When was this opportunity created?

The opportunity was created on March 14, 2024.

What is the original closing date listed for this opportunity?

The original closing date listed is January 7, 2027.

What is the maximum award amount mentioned?

The listed award ceiling is $100,000, which is the maximum award amount referenced in the provided information.

What does "investigator-initiated" mean in this context?

In this context, it means the research project is proposed and designed by the investigator (rather than being a pre-defined project topic), as long as it aligns with NIH mission areas and fits within the program limits (including the prohibition on clinical trials).

How does SuRE strengthen research capacity at an institution?

SuRE is designed to build a stronger and more sustainable research environment by supporting faculty research programs, embedding student training and mentorship into the project, creating hands-on research experiences for students, and improving the overall campus culture related to scientific investigation.

What role do students play in SuRE projects?

Based on the program description, student involvement is a key feature. The project is expected to create meaningful hands-on research opportunities for students and support mentorship and development as part of the broader goal of strengthening the institution's research environment.

Is SuRE tied to a single NIH Institute or Center?

No. The opportunity falls under multiple NIH CFDA listings, reflecting that applications can align with different NIH Institutes and Centers depending on the scientific topic.

Which CFDA listings are associated with this opportunity?

The provided information lists multiple NIH CFDA numbers associated with this opportunity: 93.113, 93.121, 93.172, 93.173, 93.242, 93.273, 93.279, 93.286, 93.361, 93.398, 93.846, 93.847, 93.853, 93.855, 93.859, 93.866, 93.867, and 93.879.

What should reviewers and program staff generally expect from a SuRE project?

The provided description indicates that reviewers and program staff typically expect the proposed work to be scientifically sound and feasible, while also clearly contributing to long-term capacity building at the institution through sustained research activity, student development, and a stronger research culture.

What does "resource-limited" mean in the context of SuRE eligibility?

The provided information uses "resource-limited" to describe colleges and universities with fewer research resources and fewer historical opportunities to compete for and sustain major federal biomedical research funding. The program is designed to strengthen research capacity in that context.

What are the key boundaries or restrictions highlighted for this opportunity?

The information highlights three major boundaries: (1) clinical trials are not allowed, (2) only domestic applicants and domestic project components are permitted, and (3) foreign organizations, non-domestic components, and foreign components are not allowed.

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